Polymers with tunable side-chain amphiphilicity as non-hemolytic antibacterial agents.
نویسندگان
چکیده
Quaternized polymers mimicking the antimicrobial peptides were created by tuning the side-chain amphiphilicity using a first-time approach of post-functionalization. They displayed excellent efficacy against pathogenic bacteria even in human plasma and membrane disruptive mode of action. The optimized polymers and degraded products were non-hemolytic.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 49 82 شماره
صفحات -
تاریخ انتشار 2013